Where do most trucks travel — and which segments pose the greatest risks for heavy freight?
The U.S. Interstate Highway System is the backbone of ground freight transportation. Every day, millions of trucks move across the country carrying food, materials, electronics, and critical cargo. But not all routes are created equal: some see the heaviest truck traffic, while others are hotspots for crashes and risk.
🚚 Top Truck Traffic Highways (by Volume)
According to the Federal Highway Administration (FHWA), the following interstate routes carry the highest average daily volumes of heavy trucks:
Highway | Segment | Trucks per Day (avg.) |
---|---|---|
I-95 | Miami – New York | 72,000+ |
I-5 | San Diego – Seattle | 60,000+ |
I-10 | Los Angeles – Jacksonville | 58,000+ |
I-40 | Barstow – Wilmington (NC) | 54,000+ |
I-80 | San Francisco – Teaneck (NJ) | 50,000+ |
💡 Key stat: Over 40% of interstate freight traffic moves along these five routes.

Most Dangerous Routes for Trucks in 2025
Truck crashes tend to concentrate on specific highway segments due to a mix of factors like weather, traffic density, urban crossings, and poor infrastructure.
🔴 1. I-95 – East Coast
Critical segment: Baltimore to Newark
Serious truck crashes/year: 1,200+ (NHTSA, 2024)
Causes: Heavy congestion, coastal fog, multilane stretches
Risk level: 🚨 Very High
🔴 2. I-10 – Southern California & Arizona
Critical segment: Los Angeles to Phoenix
Hazards: Driver fatigue, extreme heat
Danger zones: Coachella Valley, border crossings
🔴 3. I-45 – Texas
Labeled as the deadliest interstate for heavy vehicles
Segment: Houston to Dallas
Fatalities per million miles: 56 (ValuePenguin, 2024)
🔴 4. I-70 – Colorado
Mountain stretches with extreme weather
Risks: Rollovers and skids due to ice and steep grades
🔴 5. I-35 – Texas to Minnesota
High crash rate in urban areas: Austin, Dallas, Kansas City
Challenge: Mix of local and interstate traffic
What Increases Trucking Risk?
Driver fatigue: Contributes to 13% of serious crashes (FMCSA)
Weather conditions: 22% of accidents occur in rain, ice, or snow
Mixed traffic: Trucks navigating among passenger cars without dedicated lanes
Lack of infrastructure: Damaged pavement and insufficient rest stops
How Can Fleets Prevent Accidents on These Routes?
🔍 The safest fleets are adopting tools like:
AI-powered dashcams to detect distraction and fatigue
Real-time GPS monitoring with critical zone alerts
Telematics data analysis to avoid high-traffic time slots
Route-specific training with localized hazard warnings
Strategic Driving Is Key
Knowing which routes are the busiest and most hazardous is essential for every fleet manager, logistics company, and independent trucker. In 2025, with increased pressure on delivery times and growing competition, road safety is not just a legal or ethical concern — it’s a strategic and economic advantage.